Products for Research Use Only
RegisterLogin

ATF-1 Polyclonal Antibody

CAT: 0749-ABP55328-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP55328-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
ATF1 encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3) . Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of ATF1 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. ATF1 has a pseudogene on chromosome 6.
Description
Rabbit Anti-ATF-1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ATF1; Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36
Gene ID
466
Accession Number
P18846
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human ATF-1 around the non-phosphorylation site of S63
Clonality
Polyclonal
Tag
Cyclic AMP-dependent transcription factor ATF-1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
29kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ATF-1 Polyclonal Antibody detects endogenous levels of ATF-1 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Other Product Names
ATF1; Cyclic AMP-dependent transcription factor ATF-1; cAMP-dependent transcription factor ATF-1; Activating transcription factor 1; Protein TREB36
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P18846
Isotype
Rabbit IgG

Related Products

CatalogName
ABP55327-01ATF-1 (phospho Ser63) Polyclonal Antibody
ABP50725-01ATF-6β Polyclonal Antibody
ABP50723-01ATF-2 Polyclonal Antibody
ABP50724-01ATF-5 Polyclonal Antibody
ABP50726-01ATF-7 Polyclonal Antibody
ABP53806-01ATF-2 Polyclonal Antibody
ABP53808-01ATF-2 Polyclonal Antibody
ABP53503-01B-ATF Polyclonal Antibody
ABP53807-01ATF-2 Polyclonal Antibody
ABP53805-01ATF-2 Polyclonal Antibody

Alternative Products

CatalogName
JOT-AP00691-01ATF-1 Polyclonal Antibody
APRab07262-01ATF-1 Rabbit Polyclonal Antibody
40624-01ATF Polyclonal Antibody
B0411-01ATF-1 Antibody

Popular Products