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MEL-1A-R Polyclonal Antibody

CAT: 0749-ABP55288-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55288-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Description
Rabbit Anti-MEL-1A-R Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor
Gene ID
4543
Accession Number
P48039
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human MEL-1A-R at AA range: 160-240
Clonality
Polyclonal
Tag
Melatonin receptor type 1A
Applications
WB, ELISA, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MEL-1A-R Polyclonal Antibody detects endogenous levels of MEL-1A-R protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Other Product Names
MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P48039
Isotype
Rabbit IgG

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