MSH2 Polyclonal Antibody

CAT: 0749-ABP55282-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP55282-01Size:30 µL
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Background
MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E.coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Description
Rabbit Anti-MSH2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2
Gene ID
4436
Accession Number
P43246
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human MSH2 at AA range: 510-590
Clonality
Polyclonal
Tag
DNA mismatch repair protein Msh2
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
100kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MSH2 Polyclonal Antibody detects endogenous levels of MSH2 protein.
Observed Molecular Weight
100
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P43246
Isotype
Rabbit IgG

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