Products for Research Use Only

ME2 Polyclonal Antibody

CAT: 0749-ABP55218-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55218-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
Description
Rabbit Anti-ME2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ME2; NAD-dependent malic enzyme; mitochondrial; NAD-ME; Malic enzyme 2
Gene ID
4200
Accession Number
P23368
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human ME2 at AA rangle: 180-260
Clonality
Polyclonal
Tag
NAD-dependent malic enzyme mitochondrial
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
65kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ME2 Polyclonal Antibody detects endogenous levels of ME2 protein.
Observed Molecular Weight
65
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
ME2; NAD-dependent malic enzyme; mitochondrial; NAD-ME; Malic enzyme 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P23368
Isotype
Rabbit IgG