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Sovleplenib

CAT: 0607-BA9024-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0607-BA9024-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1415792-84-5
Form
A solid
Molecular Formula
C24H30N6O3S
Molecular Weight
482.60
Shipping Conditions
Blue ice
Storage Conditions
-20°C.

Chemical Information

Sovleplenib

Sovleplenib is a novel, investigational, selective small molecule inhibitor for oral administration targeting spleen tyrosine kinase (Syk). It is under investigation in clinical trial NCT03483948 (Phase I Study of Hmpl-523+azacitidine in Elderly Patients With Acute Myeloid Leukemia).

CAS Number1415792-84-5
PubChem CID71113742
IUPAC Name7-[4-(1-methylsulfonylpiperidin-4-yl)phenyl]-N-[[(2S)-morpholin-2-yl]methyl]pyrido[3,4-b]pyrazin-5-amine
Molecular FormulaC24H30N6O3S
Molecular Weight482.6
XLogP1.2
Topological Polar Surface Area118
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Heavy Atom Count34
Formal Charge0
Complexity748
SMILES
CS(=O)(=O)N1CCC(CC1)C2=CC=C(C=C2)C3=CC4=NC=CN=C4C(=N3)NC[C@@H]5CNCCO5
InChI
InChI=1S/C24H30N6O3S/c1-34(31,32)30-11-6-18(7-12-30)17-2-4-19(5-3-17)21-14-22-23(27-9-8-26-22)24(29-21)28-16-20-15-25-10-13-33-20/h2-5,8-9,14,18,20,25H,6-7,10-13,15-16H2,1H3,(H,28,29)/t20-/m0/s1
InChIKey
NJIAKNWTIVDSDA-FQEVSTJZSA-N
Chemical Structure
2D Structure
2D structure of Sovleplenib
CAS: 1415792-84-5
CID: 71113742
Formula: C24H30N6O3S
MW: 482.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight482.6
XLogP31.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass482.21001001
Monoisotopic Mass482.21001001
Topological Polar Surface Area118 Ų
Heavy Atom Count34
Formal Charge0
Complexity748
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
GTR19259622-01Sovleplenib

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