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Jun B Polyclonal Antibody

CAT: 0749-ABP54985-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54985-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
JunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice. JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML) .
Description
Rabbit Anti-Jun B Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
JUNB; Transcription factor jun-B
Gene ID
3726
Accession Number
P17275
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human Jun B around the non-phosphorylation site of S259
Clonality
Polyclonal
Tag
Transcription factor jun-B
Applications
WB, IHC, IF, IP, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
36kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Jun B Polyclonal Antibody detects endogenous levels of Jun B protein.
Observed Molecular Weight
36
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IP 2-5 ug:mg lysate; ELISA 1:20000; IF 1:50-200
Other Product Names
JUNB; Transcription factor jun-B
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P17275
Isotype
Rabbit IgG

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