2,6-Dibromophenol

• Description:

  2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda) [1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302+H312+H332

• Target:

  Calcium Channel; Fungal; Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/2-6-dibromophenol.html

• Purity:

  99.83

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OC1=C(Br)C=CC=C1Br

• Molecular Formula:

  C6H4Br2O

• Molecular Weight:

  251.91

• Precautions:

  H302+H312+H332

• References & Citations:

  [1]Hassenklöver T, et al. Bromophenols, both present in marine organisms and in industrial flame retardants, disturb cellular Ca2+ signaling in neuroendocrine cells (PC12) . Aquat Toxicol. 2006 Jan 5;76 (1) :37-45.|[2]Li B, et al. Acute Toxicities of Bromophenols to Alga and Daphina: Comparative Species Sensitivity Distribution Between Standard and Dietary Supplementation Tests. J Toxicol. 2025 May 11;2025:3399746.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [608-33-3]