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2,6-Dibromophenol

CAT: 0804-HY-Y1667-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-Y1667-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2,6-Dibromophenol (2,6-DBP) is a weak inhibitor targeting voltage-gated Ca2+ channels. 2,6-Dibromophenol has no significant effect on potassium-induced calcium elevation in PC12 cells. 2,6-Dibromophenol shows a 48 h EC50 of 2.78 mg/L for Daphnia magna and a 96 h EC50 of 9.90 mg/L for algae (Scenedesmus quadricauda) [1][2].
CAS Number
608-33-3
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Calcium Channel; Fungal; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2-6-dibromophenol.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=C(Br)C=CC=C1Br
Molecular Formula
C6H4Br2O
Molecular Weight
251.91
Precautions
H302+H312+H332
References & Citations
[1]Hassenklöver T, et al. Bromophenols, both present in marine organisms and in industrial flame retardants, disturb cellular Ca2+ signaling in neuroendocrine cells (PC12) . Aquat Toxicol. 2006 Jan 5;76 (1) :37-45.|[2]Li B, et al. Acute Toxicities of Bromophenols to Alga and Daphina: Comparative Species Sensitivity Distribution Between Standard and Dietary Supplementation Tests. J Toxicol. 2025 May 11;2025:3399746.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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