E-Ras Polyclonal Antibody

• Background :

  ERAS encodes a constitutively active member of the small GTPase Ras protein family. The ES cell expressed Ras activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. ERAS may be involved in cancer and chemotherapy resistance.

• Description :

  Rabbit Anti-E-Ras Polyclonal Antibody

• Product Name Alternative :

  ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras

• Gene ID :

  3266

• Accession Number :

  Q7Z444

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from the C-terminal region of human E-Ras at AA rangle: 160-240

• Clonality :

  Polyclonal

• Tag :

  GTPase Eras

• Applications :

  WB, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  25kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  E-Ras Polyclonal Antibody detects endogenous levels of E-Ras protein.

• Observed Molecular Weight :

  25

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.

• Other Product Names :

  ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q7Z444

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG