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HC-II Polyclonal Antibody

CAT: 0749-ABP54719-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54719-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SERPIND1 belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. SERPIND1 encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.
Description
Rabbit Anti-HC-II Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SERPIND1; HCF2; Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1
Gene ID
3053
Accession Number
P05546
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human HC-II at AA rangle: 10-90
Clonality
Polyclonal
Tag
Heparin cofactor 2
Applications
WB, IHC, IF, ELISA
Field of Research
Epigenetics
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
60kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
HC-II Polyclonal Antibody detects endogenous levels of HC-II protein.
Observed Molecular Weight
60
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
SERPIND1; HCF2; Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; HLS2; Serpin D1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P05546
Isotype
Rabbit IgG

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