GPR31 Polyclonal Antibody

CAT: 0749-ABP54607-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP54607-01Size:30 µL
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Background
GPR31 (G Protein-Coupled Receptor 31) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is HCAR3. igh-affinity receptor for 12- (S) -hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE) . 12- (S) -HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.
Description
Rabbit Anti-GPR31 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GPR31; 12- (S) -hydroxy-5; 8,10,14-eicosatetraenoic acid receptor; 12- (S) -HETE receptor; 12-HETER; G-protein coupled receptor 31
Gene ID
2853
Accession Number
O00270
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human GPR31 at AA rangle: 150-230
Clonality
Polyclonal
Tag
12- (S) -hydroxy-5,8,10,14-eicosatetraenoic acid receptor
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
33kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GPR31 Polyclonal Antibody detects endogenous levels of GPR31 protein.
Observed Molecular Weight
33
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Other Product Names
GPR31; 12- (S) -hydroxy-5; 8,10,14-eicosatetraenoic acid receptor; 12- (S) -HETE receptor; 12-HETER; G-protein coupled receptor 31
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O00270
Isotype
Rabbit IgG

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