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PA26 Polyclonal Antibody

CAT: 0749-ABP54549-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54549-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SESN1 encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The sestrin 1 mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Description
Rabbit Anti-PA26 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SESN1; PA26; SEST1; Sestrin-1; p53-regulated protein PA26
Gene ID
27244
Accession Number
Q9Y6P5
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human PA26 at AA rangle: 240-320
Clonality
Polyclonal
Tag
Sestrin-1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
57kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PA26 Polyclonal Antibody detects endogenous levels of PA26 protein.
Observed Molecular Weight
57
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
SESN1; PA26; SEST1; Sestrin-1; p53-regulated protein PA26
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9Y6P5
Isotype
Rabbit IgG

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