STK36 Polyclonal Antibody

CAT: 0749-ABP54544-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP54544-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
STK36 encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that STK36 is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants.
Description
Rabbit Anti-STK36 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog
Gene ID
27148
Accession Number
Q9NRP7
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human STK36 at AA rangle: 360-440
Clonality
Polyclonal
Tag
Serine threonine-protein kinase 36
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
170kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
STK36 Polyclonal Antibody detects endogenous levels of STK36 protein.
Observed Molecular Weight
170
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Other Product Names
STK36; KIAA1278; Serine/threonine-protein kinase 36; Fused homolog
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9NRP7
Isotype
Rabbit IgG