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GCKR Polyclonal Antibody

CAT: 0749-ABP54495-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54495-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GCKR encodes glucokinase regulator belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. GCKR is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY) .
Description
Rabbit Anti-GCKR Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GCKR; Glucokinase regulatory protein; Glucokinase regulator
Gene ID
2646
Accession Number
Q14397
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human GCKR at AA rangle: 180-260
Clonality
Polyclonal
Tag
Glucokinase regulatory protein
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
68kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GCKR Polyclonal Antibody detects endogenous levels of GCKR protein.
Observed Molecular Weight
68
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
GCKR; Glucokinase regulatory protein; Glucokinase regulator
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q14397
Isotype
Rabbit IgG

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