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TIN2 Polyclonal Antibody

CAT: 0749-ABP54487-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54487-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.
Description
Rabbit Anti-TIN2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Gene ID
26277
Accession Number
Q9BSI4
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human TIN2 at AA rangle: 40-120
Clonality
Polyclonal
Tag
TERF1-interacting nuclear factor 2
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
53kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.
Observed Molecular Weight
53
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9BSI4
Isotype
Rabbit IgG

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