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GABAA Rδ Polyclonal Antibody

CAT: 0749-ABP54433-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54433-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. GABRD encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
Description
Rabbit Anti-GABAA Rδ Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GABRD; Gamma-aminobutyric acid receptor subunit delta; GABA (A) receptor subunit delta
Gene ID
2563
Accession Number
O14764
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human GABAA rangle: Rδ at AA rangle: 110-190
Clonality
Polyclonal
Tag
Gamma-aminobutyric acid receptor subunit delta
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
51kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
GABAA Rδ Polyclonal Antibody detects endogenous levels of GABAA Rδ protein.
Observed Molecular Weight
51
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
GABRD; Gamma-aminobutyric acid receptor subunit delta; GABA (A) receptor subunit delta
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O14764
Isotype
Rabbit IgG

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