V-ATPase C2 Polyclonal Antibody

CAT: 0749-ABP54396-01Size: 30 µLDry Ice: NoHazardous: No

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CAT#:0749-ABP54396-01Size:30 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1C2 encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.

Description

Rabbit Anti-V-ATPase C2 Polyclonal Antibody

CAS Number

9007-83-4

Product Name Alternative

ATP6V1C2; V-type proton ATPase subunit C 2; V-ATPase subunit C 2; Vacuolar proton pump subunit C 2

Gene ID

245973

Accession Number

Q8NEY4

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from the Internal region of human V-ATPase C2 at AA rangle: 90-170

Clonality

Polyclonal

Tag

V-type proton ATPase subunit C 2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

48kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

V-ATPase C2 Polyclonal Antibody detects endogenous levels of V-ATPase C2 protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.

Other Product Names

ATP6V1C2; V-type proton ATPase subunit C 2; V-ATPase subunit C 2; Vacuolar proton pump subunit C 2

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q8NEY4

Isotype

Rabbit IgG

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JOT-AP09484-01	V-ATPase H Polyclonal Antibody
JOT-AP09481-01	V-ATPase C2 Polyclonal Antibody
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MBS8525841-01	V-ATPase D Polyclonal Antibody
MBS8525839-01	V-ATPase B1 Polyclonal Antibody
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V-ATPase C2 Polyclonal Antibody

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