Fc gamma RIIB/CD32b, Cynomolgus (HEK293, His)

Fc gamma RIIB/CD32b, Cynomolgus (HEK293, His)

• UNSPSC Description: Fc γ RIIB/CD32b proteins exhibit low affinity as complexes or receptors that aggregate the immunoglobulin γFc region. ITIM phosphorylated by Fc γ RIIB/CD32b recruits inositol phosphatases SHIP1 and SHIP2, inhibits Ras activation, down-regulates MAPK activity, reduces PLC-γ function, and results in PKC activation. Inhibition of MAP kinase pathway and anti-apoptotic kinase Akt inhibit cell proliferation and survival. Fc gamma RIIB/CD32b Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Fc gamma RIIB/CD32b protein, expressed by HEK293 , with C-His labeled tag.
• Type: Recombinant Proteins
• Assay Protocol: https://www.medchemexpress.com/cytokines/fc-gamma-riib-cd32b-protein-cynomolgus-217a-a-hek293-his.html
• Purity: 97.90
• Molecular Weight: 28-33 kDa
• Shipping Conditions: Dry Ice
• Storage Conditions: Stored at -80°C for 1 year