ETS1 Polyclonal Antibody

• Background:

  ETS1 encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

• Description:

  Rabbit Anti-ETS1 Polyclonal Antibody

• Product Name Alternative:

  ETS1; EWSR2; Protein C-ets-1; p54

• Gene ID:

  2113

• Accession Number:

  P14921

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from human Ets-1 around the non-phosphorylation site of T38

• Clonality:

  Polyclonal

• Tag:

  Protein C-ets-1

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  50kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  ETS1 Polyclonal Antibody detects endogenous levels of ETS1 protein.

• Observed Molecular Weight:

  50

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.

• Other Product Names:

  ETS1; EWSR2; Protein C-ets-1; p54

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P14921

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG