Dsg2 Polyclonal Antibody

• Background :

  DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.

• Description :

  Rabbit Anti-Dsg2 Polyclonal Antibody

• Product Name Alternative :

  DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC

• Gene ID :

  1829

• Accession Number :

  Q14126

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from the Internal region of human Dsg2 at AA rangle: 370-450

• Clonality :

  Polyclonal

• Tag :

  Desmoglein-2

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  140kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.

• Observed Molecular Weight :

  140

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.

• Other Product Names :

  DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q14126

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG