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Dsg2 Polyclonal Antibody

CAT: 0749-ABP54029-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54029-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
Description
Rabbit Anti-Dsg2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC
Gene ID
1829
Accession Number
Q14126
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Dsg2 at AA rangle: 370-450
Clonality
Polyclonal
Tag
Desmoglein-2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
140kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.
Observed Molecular Weight
140
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q14126
Isotype
Rabbit IgG

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