DOCK2 Polyclonal Antibody

CAT: 0749-ABP54017-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP54017-01Size:30 µL
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Background
Dedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long-term survival of allografts, suggesting that this gene may be a target for controlling transplant rejection.
Description
Rabbit Anti-DOCK2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
DOCK2; KIAA0209; Dedicator of cytokinesis protein 2
Gene ID
1794
Accession Number
Q92608
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human DOCK2
Clonality
Polyclonal
Tag
Dedicator of cytokinesis protein 2
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
DOCK2 Polyclonal Antibody detects endogenous levels of DOCK2 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
DOCK2; KIAA0209; Dedicator of cytokinesis protein 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q92608
Isotype
Rabbit IgG

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