RAGE Polyclonal Antibody

• Background :

  The advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID: 18089847) .

• Description :

  Rabbit Anti-RAGE Polyclonal Antibody

• Product Name Alternative :

  AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products

• Gene ID :

  177

• Accession Number :

  Q15109

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Synthesized peptide derived from the Internal region of human RAGE at AA range: 133-182

• Clonality :

  Polyclonal

• Tag :

  Advanced glycosylation end product-specific receptor

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  37kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  RAGE Polyclonal Antibody detects endogenous levels of RAGE protein.

• Observed Molecular Weight :

  37

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200

• Other Product Names :

  AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q15109

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG