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CYP1A2 Polyclonal Antibody

CAT: 0749-ABP53922-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53922-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CYP1A2 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.
Description
Rabbit Anti-CYP1A2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CYP1A2; Cytochrome P450 1A2; CYPIA2; Cytochrome P (3) 450; Cytochrome P450 4; Cytochrome P450-P3
Gene ID
1544
Accession Number
P05177
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human CYP1A2 at AA rangle: 300-380
Clonality
Polyclonal
Tag
Cytochrome P450 1A2
Applications
IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CYP1A2 Polyclonal Antibody detects endogenous levels of CYP1A2 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
CYP1A2; Cytochrome P450 1A2; CYPIA2; Cytochrome P (3) 450; Cytochrome P450 4; Cytochrome P450-P3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P05177
Isotype
Rabbit IgG

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