CREM Polyclonal Antibody

• Background:

  CREM encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

• Description:

  Rabbit Anti-CREM Polyclonal Antibody

• Product Name Alternative:

  CREM; cAMP-responsive element modulator; Inducible cAMP early repressor; ICER

• Gene ID:

  1390

• Accession Number:

  Q03060

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from the Internal region of human CREM at AA rangle: 50-130

• Clonality:

  Polyclonal

• Tag:

  CAMP-responsive element modulator

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  34kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  CREM Polyclonal Antibody detects endogenous levels of CREM protein.

• Observed Molecular Weight:

  34

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200

• Other Product Names:

  CREM; cAMP-responsive element modulator; Inducible cAMP early repressor; ICER

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q03060

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG