COX5b Polyclonal Antibody

• Background:

  Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX5B encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme.

• Description:

  Rabbit Anti-COX5b Polyclonal Antibody

• Product Name Alternative:

  COX5B; Cytochrome c oxidase subunit 5B; mitochondrial; Cytochrome c oxidase polypeptide Vb

• Gene ID:

  1329

• Accession Number:

  P10606

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthesized peptide derived from the N-terminal region of human COX5b at AA rangle: 30-110

• Clonality:

  Polyclonal

• Tag:

  Cytochrome c oxidase subunit 5B mitochondrial

• Applications:

  IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  COX5b Polyclonal Antibody detects endogenous levels of COX5b protein.

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200

• Other Product Names:

  COX5B; Cytochrome c oxidase subunit 5B; mitochondrial; Cytochrome c oxidase polypeptide Vb

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P10606

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG