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CYP2R1 Polyclonal Antibody

CAT: 0749-ABP53682-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53682-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CYP2R1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.
Description
Rabbit Anti-CYP2R1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CYP2R1; Vitamin D 25-hydroxylase; Cytochrome P450 2R1
Gene ID
120227
Accession Number
Q6VVX0
Reactivity
Human, Mouse, Monkey
Immunogen
Synthesized peptide derived from the Internal region of human CYP2R1 at AA rangle: 220-300
Clonality
Polyclonal
Tag
Vitamin D 25-hydroxylase
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
52kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CYP2R1 Polyclonal Antibody detects endogenous levels of CYP2R1 protein.
Observed Molecular Weight
52
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
CYP2R1; Vitamin D 25-hydroxylase; Cytochrome P450 2R1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6VVX0
Isotype
Rabbit IgG

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