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P19 Polyclonal Antibody

CAT: 0749-ABP53464-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53464-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The cyclin dependent kinase inhibitor 2D encoded by CDKN2D is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
Description
Rabbit Anti-p19 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CDKN2D; Cyclin-dependent kinase 4 inhibitor D; p19-INK4d
Gene ID
1032
Accession Number
P55273
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human p19 at AA rangle: 70-150
Clonality
Polyclonal
Tag
Cyclin-dependent kinase 4 inhibitor D
Applications
IHC, IF, WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
P19 Polyclonal Antibody detects endogenous levels of p19 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
CDKN2D; Cyclin-dependent kinase 4 inhibitor D; p19-INK4d
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P55273
Isotype
Rabbit IgG

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