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LIFR Polyclonal Antibody

CAT: 0749-ABP53335-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53335-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LIFR encodes leukemia inhibitory factor receptor alpha that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t (5;8) (p13; q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.
Description
Rabbit Anti-LIFR Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
LIFR; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118
Gene ID
3977
Accession Number
P42702
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human LIFR
Clonality
Polyclonal
Tag
Leukemia inhibitory factor receptor
Applications
WB, ELISA, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
120kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
LIFR Polyclonal Antibody detects endogenous levels of LIFR protein.
Observed Molecular Weight
120
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Other Product Names
LIFR; Leukemia inhibitory factor receptor; LIF receptor; LIF-R; CD118
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P42702
Isotype
Rabbit IgG

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