CD85d Polyclonal Antibody

CAT: 0749-ABP53326-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP53326-01Size:30 µL
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Background
LILRB2 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B2 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) . The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
Rabbit Anti-CD85d Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
LILRB2; ILT4; LIR2; MIR10; Leukocyte immunoglobulin-like receptor subfamily B member 2; LIR-2; Leukocyte immunoglobulin-like receptor 2; CD85 antigen-like family member D; Immunoglobulin-like transcript 4; ILT-4; Monocyte/macrophage immunoglobulin-like re
Gene ID
10288
Accession Number
Q8N423
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human CD85d
Clonality
Polyclonal
Tag
Leukocyte immunoglobulin-like receptor subfamily B member 2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
66kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CD85d Polyclonal Antibody detects endogenous levels of CD85d protein.
Observed Molecular Weight
66
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
LILRB2; ILT4; LIR2; MIR10; Leukocyte immunoglobulin-like receptor subfamily B member 2; LIR-2; Leukocyte immunoglobulin-like receptor 2; CD85 antigen-like family member D; Immunoglobulin-like transcript 4; ILT-4; Monocyte/macrophage immunoglobulin-like re
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8N423
Isotype
Rabbit IgG

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