CD42d Polyclonal Antibody

CAT: 0749-ABP53318-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP53318-01Size:30 µL
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Background
Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al. 1998 [PubMed: 9616133]) .
Description
Rabbit Anti-CD42d Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD42d
Gene ID
2814
Accession Number
P40197
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human CD42d
Clonality
Polyclonal
Tag
Platelet glycoprotein V
Applications
WB, IHC, IF, FC, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
62kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CD42d Polyclonal Antibody detects endogenous levels of CD42d protein.
Observed Molecular Weight
62
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
GP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD42d
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P40197
Isotype
Rabbit IgG

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