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SOD-2 Polyclonal Antibody

CAT: 0749-ABP53306-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53306-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SOD2 is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.
Description
Rabbit Anti-SOD-2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SOD2; Superoxide dismutase [Mn], mitochondrial
Gene ID
6648
Accession Number
P04179
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human SOD-2
Clonality
Polyclonal
Tag
Superoxide dismutase [Mn] mitochondrial
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
24kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
SOD-2 Polyclonal Antibody detects endogenous levels of SOD-2 protein.
Observed Molecular Weight
24
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-1:2000; ELISA 1:10000; IF 1:50-200
Other Product Names
SOD2; Superoxide dismutase [Mn], mitochondrial
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P04179
Isotype
Rabbit IgG

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