CD89 Polyclonal Antibody

• Background :

  FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

• Description :

  Rabbit Anti-CD89 Polyclonal Antibody

• Product Name Alternative :

  FCAR; CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89

• Gene ID :

  2204

• Accession Number :

  P24071

• Reactivity :

  Human

• Immunogen :

  Synthesized peptide derived from the Internal region of human CD89

• Clonality :

  Polyclonal

• Tag :

  Immunoglobulin alpha Fc receptor

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  32kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  CD89 Polyclonal Antibody detects endogenous levels of CD89 protein.

• Observed Molecular Weight :

  32

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200

• Other Product Names :

  FCAR; CD89; Immunoglobulin alpha Fc receptor; IgA Fc receptor; CD89

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P24071

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG