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OAS2 Polyclonal Antibody

CAT: 0749-ABP53267-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53267-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OAS2 encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The 2'-5'-oligoadenylate synthetase 2 is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As) . These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Description
Rabbit Anti-OAS2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
OAS2; 2'-5'-oligoadenylate synthase 2; (2-5') oligo (A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS
Gene ID
4939
Accession Number
P29728
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human OAS2
Clonality
Polyclonal
Tag
2'-5'-oligoadenylate synthase 2
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
82kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
OAS2 Polyclonal Antibody detects endogenous levels of OAS2 protein.
Observed Molecular Weight
82
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
OAS2; 2'-5'-oligoadenylate synthase 2; (2-5') oligo (A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P29728
Isotype
Rabbit IgG

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