Products for Research Use Only
RegisterLogin

RSAD2 Polyclonal Antibody

CAT: 0749-ABP53265-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP53265-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2) is a Protein Coding gene. Diseases associated with RSAD2 include influenza and encephalitis. Among its related pathways are Immune System and Interferon gamma signaling. Gene Ontology (GO) annotations related to this gene include protein self-association and iron-sulfur cluster binding. Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1) . Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR) -mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.
Description
Rabbit Anti-RSAD2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
RSAD2; CIG5; Radical S-adenosyl methionine domain-containing protein 2; Cytomegalovirus-induced gene 5 protein; Viperin; Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible
Gene ID
91543
Accession Number
Q8WXG1
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human RSAD2
Clonality
Polyclonal
Tag
Radical S-adenosyl methionine domain-containing protein 2
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
42kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
RSAD2 Polyclonal Antibody detects endogenous levels of RSAD2 protein.
Observed Molecular Weight
42
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
RSAD2; CIG5; Radical S-adenosyl methionine domain-containing protein 2; Cytomegalovirus-induced gene 5 protein; Viperin; Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8WXG1
Isotype
Rabbit IgG

Related Products

CatalogName
PPT-15084Human RSAD2 Recombinant Protein
ABP52396-01RSAD1 Polyclonal Antibody
KTE60784-01Human Radical S-adenosyl methionine domain-containing protein 2 (RSAD2) ELISA Kit
ANT-13843-100ugPolyclonal Antibody
ANT-15047-100ugWAS Polyclonal Antibody
ANT-15047-50ugWAS Polyclonal Antibody
ANT-13843-50ugPolyclonal Antibody
ABP51603-01IKKBeta Polyclonal AntibodyIKKβ Polyclonal Antibody
ABP50715-01AR-Beta2 Polyclonal AntibodyAR-β2 Polyclonal Antibody
ANT-13281-50ugMRFAP1 Polyclonal Antibody

Alternative Products

CatalogName
GTR18046134-01RSAD2 polyclonal antibody
MBS9466483-01RSAD2 Rabbit Polyclonal Antibody
GTR18379511RSAD2 Rabbit Polyclonal Antibody (HRP)
GWB-B3B7BERSAD2 Antibody

Popular Products