Products for Research Use Only

Syntaxin 1 Polyclonal Antibody

CAT: 0749-ABP53171-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53171-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
STX1A encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein) -Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc) . Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
Rabbit Anti-Syntaxin 1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
STX1A; STX1; Syntaxin-1A; Neuron-specific antigen HPC-1
Gene ID
6804
Accession Number
Q16623
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Syntaxin 1
Clonality
Polyclonal
Tag
Syntaxin-1A
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
30kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Syntaxin 1 Polyclonal Antibody detects endogenous levels of Syntaxin 1 protein.
Observed Molecular Weight
30
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
STX1A; STX1; Syntaxin-1A; Neuron-specific antigen HPC-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q16623
Isotype
Rabbit IgG