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P73 Polyclonal Antibody

CAT: 0749-ABP53074-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53074-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TP73 encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.
Description
Rabbit Anti-p73 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
Gene ID
7161
Accession Number
O15350
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human p73 around the non-acetylation site of K321
Clonality
Polyclonal
Tag
Tumor protein p73
Applications
WB, IHC, IF, ELISA
Field of Research
Cancer#Cell Biology #Epigenetics
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
P73 Polyclonal Antibody detects endogenous levels of p73 protein.
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O15350
Isotype
Rabbit IgG

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