CD207 Polyclonal Antibody

CAT: 0749-ABP53006-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP53006-01Size:30 µL
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Background
C-type lectin domain family 4 member K encoded by CD207 is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Description
Rabbit Anti-CD207 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
Gene ID
50489
Accession Number
Q9UJ71
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human CD207
Clonality
Polyclonal
Tag
C-type lectin domain family 4 member K
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
38kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CD207 Polyclonal Antibody detects endogenous levels of CD207 protein.
Observed Molecular Weight
38
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UJ71
Isotype
Rabbit IgG

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