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SNAP 23 Polyclonal Antibody

CAT: 0749-ABP52962-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52962-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Description
Rabbit Anti-SNAP 23 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SNAP23; Synaptosomal-associated protein 23; SNAP-23; Vesicle-membrane fusion protein SNAP-23
Gene ID
8773
Accession Number
O00161
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human SNAP 23
Clonality
Polyclonal
Tag
Synaptosomal-associated protein 23
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
25kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
SNAP 23 Polyclonal Antibody detects endogenous levels of SNAP 23 protein.
Observed Molecular Weight
25
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200
Other Product Names
SNAP23; Synaptosomal-associated protein 23; SNAP-23; Vesicle-membrane fusion protein SNAP-23
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O00161
Isotype
Rabbit IgG

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