P2X3 Polyclonal Antibody

CAT: 0749-ABP52942-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP52942-01Size:30 µL
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Background
The product of P2RX3 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
Description
Rabbit Anti-P2X3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor
Gene ID
5024
Accession Number
P56373
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human P2X3
Clonality
Polyclonal
Tag
P2X purinoceptor 3
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
44kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
P2X3 Polyclonal Antibody detects endogenous levels of P2X3 protein.
Observed Molecular Weight
44
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200
Other Product Names
P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P56373
Isotype
Rabbit IgG

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