FGF-18 Polyclonal Antibody

• Background:

  Fibroblast growth factor 18 encoded by FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

• Description:

  Rabbit Anti-FGF-18 Polyclonal Antibody

• Product Name Alternative:

  FGF18; Fibroblast growth factor 18; FGF-18; zFGF5

• Gene ID:

  8817

• Accession Number:

  O76093

• Reactivity:

  Human, Mouse, Rat, Sheep

• Immunogen:

  Synthesized peptide derived from the C-terminal region of human FGF-18

• Clonality:

  Polyclonal

• Tag:

  Fibroblast growth factor 18

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  28kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  FGF-18 Polyclonal Antibody detects endogenous levels of FGF-18 protein.

• Observed Molecular Weight:

  28

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200

• Other Product Names:

  FGF18; Fibroblast growth factor 18; FGF-18; zFGF5

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/O76093

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG