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CA IV Polyclonal Antibody

CAT: 0749-ABP52859-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52859-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA4 encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport.
Description
Rabbit Anti-CA IV Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CA4; Carbonic anhydrase 4; Carbonate dehydratase IV; Carbonic anhydrase IV; CA-IV
Gene ID
762
Accession Number
P22748
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human CA IV
Clonality
Polyclonal
Tag
Carbonic anhydrase 4
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
35kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CA IV Polyclonal Antibody detects endogenous levels of CA IV protein.
Observed Molecular Weight
35
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
CA4; Carbonic anhydrase 4; Carbonate dehydratase IV; Carbonic anhydrase IV; CA-IV
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P22748
Isotype
Rabbit IgG

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