RSL3-4-Me

RSL3-4-Me

• CAS Number: 3049087-33-1
• UNSPSC Description: RSL3-4-Me is the active control of the target protein ligand Demethyl-RSL3 (HY-135832), which can be used for the synthesis of PROTAC [1].
• Target Antigen: Ligands for Target Protein for PROTAC
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/rsl3-4-me.html
• Smiles: O=C(OC)[C@@H]1N(C(CC)=O)[C@@H](C2=CC=C(C(O)=O)C=C2)C3=C(C(C=CC=C4)=C4N3)C1
• Molecular Weight: 406.43
• References & Citations: [1]Zheng C, et al. Structure-activity relationship study of RSL3-based GPX4 degraders and its potential noncovalent optimization. Eur J Med Chem. 2023 Jul 5;255:115393.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported