TAP Polyclonal Antibody

CAT: 0749-ABP52557-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP52557-01Size:30 µL
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Background
NXF1 is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2) -like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The nuclear RNA export factor 1 of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly (A) + RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-TAP Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
NXF1; TAP; Nuclear RNA export factor 1; Tip-associated protein; Tip-associating protein; mRNA export factor TAP
Gene ID
10482
Accession Number
Q9UBU9
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human TAP at AA range: 1-80
Clonality
Polyclonal
Tag
Nuclear RNA export factor 1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
TAP Polyclonal Antibody detects endogenous levels of TAP protein.
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
NXF1; TAP; Nuclear RNA export factor 1; Tip-associated protein; Tip-associating protein; mRNA export factor TAP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UBU9
Isotype
Rabbit IgG

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