RegisterLogin

Strad Polyclonal Antibody

CAT: 0749-ABP52525-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP52525-01Size:30 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
STE20-related kinase adapter protein alpha encoded by STRADA contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a 'pseudokinase'. STE20-related kinase adapter protein alpha forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25) . The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.
Description
Rabbit Anti-Strad Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
STRADA; LYK5; STRAD; STE20-related kinase adapter protein alpha; STRAD alpha; STE20-related adapter protein; Serologically defined breast cancer antigen NY-BR-96
Gene ID
92335
Accession Number
Q7RTN6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human Strad at AA range: 30-110
Clonality
Polyclonal
Tag
STE20-related kinase adapter protein alpha
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
46kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Strad Polyclonal Antibody detects endogenous levels of Strad protein.
Observed Molecular Weight
46
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
STRADA; LYK5; STRAD; STE20-related kinase adapter protein alpha; STRAD alpha; STE20-related adapter protein; Serologically defined breast cancer antigen NY-BR-96
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q7RTN6
Isotype
Rabbit IgG

Related Products

CatalogName
ABP53288-01Stra8 Polyclonal Antibody
ANT-14589-50ugSTRAP Polyclonal Antibody
ANT-14589-100ugSTRAP Polyclonal Antibody
ANT-13843-100ugPolyclonal Antibody
ANT-13843-50ugPolyclonal Antibody
ANT-15047-50ugWAS Polyclonal Antibody
ANT-15047-100ugWAS Polyclonal Antibody
ABP51603-01IKKBeta Polyclonal AntibodyIKKβ Polyclonal Antibody
ABP50715-01AR-Beta2 Polyclonal AntibodyAR-β2 Polyclonal Antibody
ABP56765-01CaSR Polyclonal Antibody

Alternative Products

CatalogName
UB-GEN-14771Strad Polyclonal Antibody
11-8100-100Polyclonal Antibody to STRAD
APRab18407-01Strad Rabbit Polyclonal Antibody
ABF0572STRAD Antibody

Popular Products