Stat4 Polyclonal Antibody

• Background :

  Signal transducer and activator of transcription 4 encoded by STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

• Description :

  Rabbit Anti-Stat4 Polyclonal Antibody

• Product Name Alternative :

  STAT4; Signal transducer and activator of transcription 4

• Gene ID :

  6775

• Accession Number :

  Q14765

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from human Stat4 around the non-phosphorylation site of Y693

• Clonality :

  Polyclonal

• Tag :

  Signal transducer and activator of transcription 4

• Applications :

  WB, IHC, IF, IP, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  85kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  Stat4 Polyclonal Antibody detects endogenous levels of Stat4 protein.

• Observed Molecular Weight :

  85

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IP 2-5 ug:mg lysate; ELISA 1:5000; IF 1:50-200

• Other Product Names :

  STAT4; Signal transducer and activator of transcription 4

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q14765

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG