Stat2 Polyclonal Antibody

CAT: 0749-ABP52511-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP52511-01Size:30 µL
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Background
Signal transducer and activator of transcription 2 encoded by STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
Rabbit Anti-Stat2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
STAT2; Signal transducer and activator of transcription 2; p113
Gene ID
6773
Accession Number
P52630
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human Stat2 around the non-phosphorylation site of Y690
Clonality
Polyclonal
Tag
Signal transducer and activator of transcription 2
Applications
WB, IP, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
113kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Stat2 Polyclonal Antibody detects endogenous levels of Stat2 protein.
Observed Molecular Weight
113
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Other Product Names
STAT2; Signal transducer and activator of transcription 2; p113
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P52630
Isotype
Rabbit IgG

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