POT1 Polyclonal Antibody

• Background :

  POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.

• Description :

  Rabbit Anti-POT1 Polyclonal Antibody

• Product Name Alternative :

  POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein

• Gene ID :

  25913

• Accession Number :

  Q9NUX5

• Reactivity :

  Human, Monkey

• Immunogen :

  Synthesized peptide derived from the Internal region of human POT1

• Clonality :

  Polyclonal

• Tag :

  Protection of telomeres protein 1

• Applications :

  WB, IHC

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  70kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.

• Observed Molecular Weight :

  70

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300

• Other Product Names :

  POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q9NUX5

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG