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POT1 Polyclonal Antibody

CAT: 0749-ABP52246-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52246-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.
Description
Rabbit Anti-POT1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
Gene ID
25913
Accession Number
Q9NUX5
Reactivity
Human, Monkey
Immunogen
Synthesized peptide derived from the Internal region of human POT1
Clonality
Polyclonal
Tag
Protection of telomeres protein 1
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.
Observed Molecular Weight
70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9NUX5
Isotype
Rabbit IgG

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