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PDK1 Polyclonal Antibody

CAT: 0749-ABP52169-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52169-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for PDK1.
Description
Rabbit Anti-PDK1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
PDK1; PDHK1; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; mitochondrial; Pyruvate dehydrogenase kinase isoform 1
Gene ID
5163
Accession Number
Q15118
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human PDK1 at AA range: 80-160
Clonality
Polyclonal
Tag
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 mitochondrial
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
50kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PDK1 Polyclonal Antibody detects endogenous levels of PDK1 protein.
Observed Molecular Weight
50
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
PDK1; PDHK1; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1; mitochondrial; Pyruvate dehydrogenase kinase isoform 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q15118
Isotype
Rabbit IgG

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