MerTK Polyclonal Antibody

CAT: 0749-ABP51780-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP51780-01Size:30 µL
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Background
MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine-protein kinase mer, with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .
Description
Rabbit Anti-MerTK Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK
Gene ID
10461
Accession Number
Q12866
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human MerTK at AA range: 10-90
Clonality
Polyclonal
Tag
Tyrosine-protein kinase Mer
Applications
WB, ELISA, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
110kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MerTK Polyclonal Antibody detects endogenous levels of MerTK protein.
Observed Molecular Weight
110
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Other Product Names
MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q12866
Isotype
Rabbit IgG

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