MerTK Polyclonal Antibody

• Background :

  MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine-protein kinase mer, with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

• Description :

  Rabbit Anti-MerTK Polyclonal Antibody

• Product Name Alternative :

  MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

• Gene ID :

  10461

• Accession Number :

  Q12866

• Reactivity :

  Human, Rat, Mouse

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human MerTK at AA range: 10-90

• Clonality :

  Polyclonal

• Tag :

  Tyrosine-protein kinase Mer

• Applications :

  WB, ELISA, IHC

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  110kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  MerTK Polyclonal Antibody detects endogenous levels of MerTK protein.

• Observed Molecular Weight :

  110

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000

• Other Product Names :

  MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q12866

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG