JAK1 Polyclonal Antibody

CAT: 0749-ABP51656-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP51656-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
JAK1 encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. Tyrosine-protein kinase JAK1 phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-JAK1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1
Gene ID
3716
Accession Number
P23458
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human JAK1 around the non-phosphorylation site of Y1022
Clonality
Polyclonal
Tag
Tyrosine-protein kinase JAK1
Applications
IF, WB, IP, IHC, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
132kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
JAK1 Polyclonal Antibody detects endogenous levels of JAK1 protein.
Observed Molecular Weight
132
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200; WB 1:200-1:1000; IHC 1:100-1:300; ELISA 1:10000; Not yet tested in other applications
Other Product Names
JAK1; JAK1A; JAK1B; Tyrosine-protein kinase JAK1; Janus kinase 1; JAK-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P23458
Isotype
Rabbit IgG

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