IGFBP3 Polyclonal Antibody

• Background:

  IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes Insulin-like growth factor-binding protein 3 with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Description:

  Rabbit Anti-IGFBP3 Polyclonal Antibody

• Product Name Alternative:

  IGFBP3; IBP3; Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3

• Gene ID:

  3486

• Accession Number:

  P17936

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from human IGFBP3 around the non-phosphorylation site of S183

• Clonality:

  Polyclonal

• Tag:

  Insulin-like growth factor-binding protein 3

• Applications:

  WB, IHC, IF, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  31kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  IGFBP3 Polyclonal Antibody detects endogenous levels of IGFBP3 protein.

• Observed Molecular Weight:

  31

• Formulation:

  Liquid solution

• Buffer pH:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:100-500; IF/ICC1:100-500; ELISA 1:5000-20000

• Other Product Names:

  IGFBP3; IBP3; Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P17936

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG